Blog Post

Osteoarthritis - 'Wear and Tear' in Joints

  • by Joanna Blair
  • 22 Nov, 2023
Osteoarthritis in joints
Common Places of Osteoarthritis Within Joints
The term 'wear and tear' is used to refer to joints with arthritis. Osteoarthritis is a degenerative condition of the articular joints and presents in more than one joint within the body. The condition affects each individual differently by causing no symptoms at all but signs are present or cause a gradual change to how joints and muscles feel, especially during specific times of the day. Approximately 80% of older adults at the age of 55 years and older have evidence of osteoarthritis on X-ray and of these an estimated 60% experience symptoms (8). Post-menopausal women have an increased incidence of knee osteoarthritis compared to men (6, 9).

The most commonly affected joints are: 
  • Knees - Knee osteoarthritis is more usual in older and obese populations with the epidemicity of knee osteoarthritis in females ( 10.3 % ) being higher than that in males ( 5.7 % ) (7).
  • Neck
  • Lower back 
  • Hands and fingers 
The symptoms of the condition depend upon the severity of the condition but they may include: 
  • Pain
  • Stiffness 
  • Joint swelling 
  • Crepitus or crunchy grinding sound of the joint

Primary & Secondary OA  

Osteoarthritis is also known as degenerative joint disease (DJD) that creates joint stiffness and pain (NHS). In the UK approximately one in 10 adults aged 20 years or older have symptomatic GP clinically diagnosed OA, with the knee joint being the most prevalent (9).
There are two main types of osteoarthritis:

  • Primary OA: Most common form with no known (idiopathic) cause and primarily affects the fingers, thumbs, spine, hips, knees, and big toe.
  • Secondary OA: Occurs with a pre-existing joint abnormality or be caused by injury or trauma from repetitive strain from e.g. a manual job or sports-related activity. Inflammatory arthritis is another example such as rheumatoidpsoriatic, or gout; infectious arthritis; genetic joint disorders, such as Ehlers-Danlos (also known as hypermobility or "double-jointed"), congenital joint disorders or metabolic joint disorders (9).

Interestingly, the incidence of OA may differ geographically within the UK with Scotland and the middle regions of England having a higher incidence compared to the rest of the country (8). The reasons for regional variation could be differences in socio-economic conditions, lifestyles and health activity behaviours. A higher prevalence of OA in the Northern regions largely matched the obesity distribution of the UK compared to the South which is a risk factor for the deverlopment of OA (9).
Osteoarthritis within the knee
Different Stages of Osteoarthritis Within the Knee

Who is at Risk For Developing Osteoarthritis? 

Main risk factors that increase the chance of developing osteoarthritis: 
  • Obesity - Obese men and women are 4 to 5 times more at risk of developing OA within the knee.
  • Diabetes 
  • Hyperlipidemia (high cholesterol and elevated lipids)
  • Low estrogen levels as experienced by post-menopausal women 
  • Genetics: hereditary conditions such as Ehlers-Danlos syndrome or joint hypermobility can contribute to OA. 
  • Abnormal biomechanics 
  • Smoking - studies showing strong evidence that smoking is positively associated with the prevalence of OA (8). 

What Is Considered Good Exercise to do For Osteoarthritis? 

Activities that maintain flexibility, muscle strength, and coordination protect the cartilaginous surfaces and help to maintain joint function in joints that have already been injured and in which arthritic changes have developed or are developing. The forms of exercise that meet these criteria include bicycling, weightlifting (with emphasis on closed-kinetic-chain exercises) and pool exercises.

The Weather & Osteoarthritis

Weather conditions appear to be associated with OA pain, however, studies tend to be inconclusive or have inconsistent findings (9). For the specific meteorological condition, quantitative analysis showed a moderate correlation between OA pain and temperature or Barometric pressure, with relative humidity has a weak correlation. 

One study found there to be no association between rainfall on the day of the appointment or rainfall during the week or preceding week and proportion of joint and back. This was concluded after having analysed millions of outpatient appointments and visits of older Americans aged over 65 years old during 2008- 12 including those with rheumatoid arthritis (4). 

Diet & OA 

There are various studies that conclude A high fat diet exacerbates the progression of osteoarthritis in mice metabolic changes and systemic inflammation brought about by a high fat diet (HFD) appear to be key players in the onset and progression of OA (7). 

Several studies show that obesity causes certain metabolic factors that induce the release of specific cytokines (proteins that help control inflammation), such as IL-6, CCL2 and IL-8, proinflammatory adipokines (cytokines produced via adipose tissue) nitric oxide, and metalloproteinases that contribute to the degradation of joint cartilage (1).

There seems to be a mixed view on whether statins can help the development of osteoarthritis, although most studies have found a significant reduction in the risk of developing OA and a reduced risk of radiographic progression in statin users vs. non-users (4). 

How Physical Therapy Can Help

Conventional treatments for OA include nonsteroidal anti inflammatory (NSAIDs) drugs and COX inhibitors, moderate exercise such as walking, light weights and aerobic activity and eventually surgery to repair joints. 

Massage Therapy 

Massage therapy may diminish symptoms and improve the course of OA by increasing local circulation to the affected joints, improve tone of supportive musculature, enhance joint flexibility and relieve pain (10).  

A study by Perlman (2018) concluded that 8 weeks of massage provided a statistically and clinically significant improvement of osteoarthritic symptoms by reducing pain,  stiffness, timed 50-foot walk and improving physical function compared to a control group in adults with knee osteoarthritis. 

References

1. Baures, M. B., Ivorra, I. M. (2019) Mediterranean Diet and Osteoarthritis, Reumatol Clin., 15:125–126.

2. Cleveland Clinic https://my.clevelandclinic.org/health/diseases/5599-osteoarthritis [online] last visited 1/10/2023.

3. Heidari, B., Babaei, M., Yosefghahri, B. (2021) Prevention of Osteoarthritis Progression by Statins, Targeting Metabolic and Inflammatory Aspects: A Review, Mediterr J Rheumatol., 32 (3): 227-236. 


4. Jena, A. B., Olenski, A. R., Molitor, D., Miller, N. (2017) Association Between Rainfall and Diagnoses of Joint or Back Pain: Retrospective Claims Analysis, BMJ: 1-4.

5. Perlman, A., Fogerite, S. G., Glass,O.,  Bechard, E., Ali, A., Njike, V. Y. (2019) Efficacy and Safety of Massage for Osteoarthritis of the Knee: a Randomized Clinical Trial, J. Get Intern Med., 34 (3): 379–386.

6. Sandmeiser, R. H. (2000) Osteoarthritis and Exercise: Does Increased Activity Wear Out Joints? Perm J., 4 (4): 26–28.

7. Sansone, V., Applefield, R. C., Luca, De. P., Pecoraro, V., Gianola, S., Pascale, W., Pascale, V. (2019) Does a high-fat diet affect the development and progression of osteoarthritis in mice? A Systemic Review, 8; 12: 582-592.

8. Swain, S., Sarmanova, A., Mallen, C., Kuo, C. F., Coupland, C., Doherty, M., Zhang, W. (2020)  

Trends in incidence and prevalence of osteoarthritis in the United Kingdom: findings from the Clinical Practice Research Datalink (CPRD), Osteoarthritis and Cartilage, 28; 6: 792-801. 

9. Wang, L., Xu, Q., Chen, Y., Zhu. Z., Cao, Y. (2023) Associations between weather conditions and osteoarthritis pain: a systematic review and meta-analysis, 55; (1). 

10. Yu, C. (2023) Research progress in the treatment of Knee Osteoarthritis, Bio Web of Conferences, 59: 1-6. 

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